Abstract: The study of refined separation of fluid catalytic cracking (FCC) gasoline fractions is an important means to reduce the benzene content in gasoline. Owing to the high benzene content in the middle fraction of FCC gasoline, separating FCC gasoline into light, middle, and heavy fractions, benzene and non-benzene components in FCC gasoline can be effectively separated to meet the requirements for benzene content in the VIB standard for automotive gasoline. The separation technology of using distillation column or stripping column to separate gasoline is a commonly used technique, but it has problems such as complex process, high reflux ratio, and high energy consumption. In this work, based on the existing stripping column for removing benzene from FCC gasoline in a catalytic cracking unit of a certain Sinopec refinery, stripping column scheme for removing benzene is studied by simulating and optimizing using Aspen software, and the distillation column scheme is studied under the same feed conditions. We proposing comparison of two processes for separating benzene: stripping column or distillation column. The technical performance is systematically evaluated. The results showed that using distillation separation and benzene-removed technology to treat FCC gasoline reduces the volume fraction of benzene from 1.15 v% to below 0.7 v%, reflux ratio and energy consumption are 0.45 and 5.486 kg of standard oil per ton of gasoline lower than those of stripping column scheme, respectively. Distillation method has more advantages in separation accuracy, energy consumption control, and benzene-removed efficiency. This work can provide some guidance for refinery to solve the problem of excessive benzene content in gasoline.