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  • ISSN 1006-3080
  • CN 31-1691/TQ

用于前列腺冷冻消融的电加热尿道保温装置

赵红莉 钱彬 徐彬凯 蓝闽波

赵红莉, 钱彬, 徐彬凯, 蓝闽波. 用于前列腺冷冻消融的电加热尿道保温装置[J]. 华东理工大学学报(自然科学版), 2019, 45(6): 891-898. doi: 10.14135/j.cnki.1006-3080.20180830004
引用本文: 赵红莉, 钱彬, 徐彬凯, 蓝闽波. 用于前列腺冷冻消融的电加热尿道保温装置[J]. 华东理工大学学报(自然科学版), 2019, 45(6): 891-898. doi: 10.14135/j.cnki.1006-3080.20180830004
ZHAO Hongli, QIAN Bin, XU Binkai, LAN Minbo. Apparatus for Electrical Urethral Heater Used in Prostate Cryoablation[J]. Journal of East China University of Science and Technology, 2019, 45(6): 891-898. doi: 10.14135/j.cnki.1006-3080.20180830004
Citation: ZHAO Hongli, QIAN Bin, XU Binkai, LAN Minbo. Apparatus for Electrical Urethral Heater Used in Prostate Cryoablation[J]. Journal of East China University of Science and Technology, 2019, 45(6): 891-898. doi: 10.14135/j.cnki.1006-3080.20180830004

用于前列腺冷冻消融的电加热尿道保温装置

doi: 10.14135/j.cnki.1006-3080.20180830004
基金项目: 上海市科委“科技创新行动计划”(15441904100)
详细信息
    作者简介:

    赵红莉(1978-),女,副研究员,研究方向为生物传感器。E-mail:honglizhao@ecust.edu.cn

    通讯作者:

    蓝闽波,E-mail:minbolan@ecust.edu.cn

  • 中图分类号: R318.52

Apparatus for Electrical Urethral Heater Used in Prostate Cryoablation

  • 摘要: 在标准导尿管的基础上,改装了一种电加热尿道保温装置,以降低医生手术中的操作和判断困难,并对该装置进行了模拟计算和体外实验测试。在使用高精度的PID控制器控制温度的同时,研究了不同加热功率对保温装置最低壁温的影响,并与水热式保温装置进行比较。体外实验中,在加热功率为9 W和使用两把冷冻消融刀的工作环境下,在冷冻30 min后保温管表面最低温度仍然能保证高于细胞致死温度(−22 ℃)。电加热尿道保温装置是一种应对冷冻手术中尿道低温损伤的有效方式。

     

  • 图  1  尿道保温控制装置及尿道保温管样品

    Figure  1.  Urethral thermal insulation controller appratus and insulation pipe sample

    图  2  尿道三维保温模型及其网格划分示意图

    Figure  2.  Heater model and 3-D mesh generation diagram of urethral

    图  3  体外实验装置布局示意图

    Figure  3.  Layout of the experiments in vitro

    图  4  不同壁厚时尿道管壁处温度变化

    Figure  4.  Temperature variation at urethral surface with different wall thicknesses

    图  5  不同粗细电阻丝对尿道管壁处温度的影响

    Figure  5.  Influences of the different resistance wires on urethral surface temperature

    图  6  两把冷刀时温度场和电压变化

    Figure  6.  Variation of temperature and voltage with two cryoprobes interfered

    图  7  水热和电加热保温管在冷刀介入消融时的温度变化

    Figure  7.  Temperature variation of electrical urethral heater and urethral warmer with cryoprobe interfered

    图  8  P=7 W时电加热尿道保温装置冷冻循环后保温装置表面温度变化情况

    Figure  8.  Urethral heater surface temperature variation after cycling of cryoablation at P=7 W

    图  9  P=9 W时电加热尿道保温装置冷冻循环后保温装置表面温度变化情况

    Figure  9.  Urethral heater surface temperature variation after cycling of cryoablation at P=9 W

    图  10  P为11 W时电加热尿道保温装置冷冻循环后保温装置表面温度变化情况

    Figure  10.  Urethral heater surface temperature variation after cycling of cryoablation at P=11 W

    表  1  仿真分析中明胶,康铜及硅胶参数

    Table  1.   Simulation analysis parameters of gelatin, constantan and silica gel

    Typesk/(W·m−1·K−1)Cb/(J·kg−1·K−1)σ/(S·m−1)ρ/(kg·m−3)
    −125 ℃≤T <
    −22 ℃
    −22 ℃≤T <
    −2 ℃
    −2 ℃≤T <
    −40 ℃
    −125 ℃≤T <
    −2 ℃
    −2 ℃≤T <
    0 ℃
    0 ℃≤T <
    5 ℃
    5 ℃≤T <
    50 ℃
    Φ0.10 mmΦ0.15 mmΦ0.30 mm
    Gelatin−0.009 1T+
    1.220 6
    −0.045 8T+
    0.413 5
    0.50521.926T+
    400 1.9
    16 973T+
    37 904
    −6 807.2T +
    37 904
    −9.657 1T +
    3 916.3
    0.3330.3330.3331 060
    Constantan20.920.920.94104104104102.51×1055.24×1055.05×1058 900
    Silicagel0.350.350.35270270270270InfinityInfinityInfinity1 314
    下载: 导出CSV

    表  2  不同功率下,0 ℃和−22 ℃等温线处最小直径DT及尿道管壁表面终温

    Table  2.   Minimum diameter (DT) of the 0 ℃ and −22 ℃ isotherm and the urethral surface final final temperature heated with different powers

    Power/WDT/mmFinal temperatme/℃
    0 ℃−22 ℃
    1121.7217.91−7.6
    921.8618.10−9.3
    722.0218.40−16.2
    522.1918.75−22.3
    Off25.7019.00−26.5
    下载: 导出CSV
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出版历程
  • 收稿日期:  2018-08-30
  • 网络出版日期:  2019-10-09
  • 刊出日期:  2019-12-01

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