The synthesis of 2,4-difluoro-5-chloro-6-methyl pyrimidine and its derived reactive dyes

Under normal pressure, taking 2, 4, 5-trichloro-6-methyl pyrimidine as a raw material, using nitrobenzene as a solvent and anhydrous potassium fluoride as a fluorinating agent, 2,4-difluoro-5-chloro-6-methyl pyrimidine (designated as DCMP) was synthesized with purity 92% and yield 70%. The DCMP was used as a reactive group, a series of new reactive dyes were resulted. These new dyes formed offer excellent properties for calico dyeing and printing.