Studies of Phase Transfer Catalysis for N-Alkylation of 2-Methylindole

Studies of Phase Transfer Catalysis for N-Alkylation of 2-Methylindole[J]. Journal of East China University of Science and Technology, 1994, (5).

Citation:

Studies of Phase Transfer Catalysis for N-Alkylation of 2-Methylindole[J]. Journal of East China University of Science and Technology, 1994, (5).

Citation:

Studies of Phase Transfer Catalysis for N-Alkylation of 2-Methylindole[J]. Journal of East China University of Science and Technology, 1994, (5).

Abstract

With the action of phase transfer catalyst(PTC),2-methylindole was N-alky-lated.The effects of different PTC,reacting time,temperature,the concentration of potassium hydroxide and the bromoethane amout on the reaction were studied.The selection of N,C-alkylation was explained theoretically. The relationship of concentration and structures of the catalyst to the reacting rate have been studied quantitatively.

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