Effect of Calcium Gluconate on Inosine Fermentation
-
Graphical Abstract
-
Abstract
During the inosine flask fermentation process,addition of 10 g/L calcium gluconate in basal medium was benificial to inosine synthesis and cell growth.This may be ascribed to the induction of glucose kinase synthesis,leading to the improvement of hexose monophosphate(HMP) shunt flux and its specific activity greatly.Inosine yield increased from(10.76) g/L to(18.36) g/L.
-
-