Synthesis and Degradation of Photopolymerisable Crosslinked Polyanhydride

Dimethacrylic sebacic anhydride (MSA) and dimethacrylic 1,6-bis(p-carboxyphenoxy)hexane (MCPH) were synthesized by methacrylic anhydride (or methacryloyl chloride) and nontoxic diacids, and their structures were charactered by IR and ()~1H-NMR. The results show that MSA directly synthesized by anhydride and MCPH synthesized by chloride are in accordance with the strucutres of polyanhydride monomers. These multifunctional monomers are photopolymerized using ultraviolet light to produce highly crosslinked polyanhydride networks. By copolymerizing varying amounts of MSA and MCPH, the degradation rate of the network is controlled from 4 d to 70 d.