Synthesis of [5-(4-Formamidino-Benzyl)-2,4-Dioxo-Imidazolidin-3-yl]-Acetyl-L-Aspartyl-L-Valin(9)[J]. Journal of East China University of Science and Technology, 1995, (4).
Citation:
Synthesis of [5-(4-Formamidino-Benzyl)-2,4-Dioxo-Imidazolidin-3-yl]-Acetyl-L-Aspartyl-L-Valin(9)[J]. Journal of East China University of Science and Technology, 1995, (4).
Synthesis of [5-(4-Formamidino-Benzyl)-2,4-Dioxo-Imidazolidin-3-yl]-Acetyl-L-Aspartyl-L-Valin(9)[J]. Journal of East China University of Science and Technology, 1995, (4).
Citation:
Synthesis of [5-(4-Formamidino-Benzyl)-2,4-Dioxo-Imidazolidin-3-yl]-Acetyl-L-Aspartyl-L-Valin(9)[J]. Journal of East China University of Science and Technology, 1995, (4).
Synthesis of 5-(4-Formamidino-Benzyl)-2,4-Dioxo-Imidazolidin-3-yl-Acetyl-L-Aspartyl-L-Valin(9)
According to the mechanism of the inhibiting action of peptlue Arg-Gly-Asp onplatelet aggregation. Peptide(9)was designed and synthesized.Results of biologic tests showedinhibiting action of(9)on platelet aggregation was the most potent.Its activity was strongerthan that of analogues in comparison with that of IC_(50).
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