肉桂醛与氰化钠/吗啡啉的缩合反应及产物结构分析
Structure Analysis of the Products Obtained from Condensation of Cinnamaldehyde, Sodium Cyanide, and Morpholine
-
摘要: 肉桂醛与氰化钠,吗啡啉在对甲苯磺酸的存在下一步缩合生成2-苯基-4-(4-吗啡啉基)-2-丁烯腈,反应条件温和,收率高达86% ̄87%,其结构经光谱分析得到确定。Abstract: Three component condensation of cinnamaldehyde, sodium cyanide, and morpholine in the presence of p toluenesulfonic acid, results in an expeditious synthesis of 1 phenyl 4 (4 morpholinyl) 2 butanenenitrile, which may be used in a variety of organic synthesis.