Abstract: 3-Layer BP neural network was used to simulate entrained-flow pulverized coal gasifier. The simulated results of gasifier by the way of Gibbs free energy minimization were used as training samples of BP neural networks, and the trained BP neural network model could accurately predict these simulated data. Meanwhile, actual operating data of Shell gasifier and the first domestic pilot plant of pulverized gasification were used as training samples of BP neural networks, and the trained BP neural network model could predict actual operating data.