Abstract: Distillation with simultaneous chemical reaction represents a special area of distillation technology, and its economical advantages have been proved. The objective of this study is to present a computation method for handling chemical reaction in an equillibrium stage device. Reported here is a technique based on the Newton-Raphson method for solving the model equations which describe distillation with simultaneous reaction. Mole fractions of components x_(ij) and vapour flow rates V_i on eaeh stage are selected as iterative variables. An outer iteration loop and an inner iteration loop are involved. The inner loop is for x_(ij) and the outer one for V_j. The Newton-Raphson method is used for the convergence of the inner loop with material balance equations being residual functions, this procedure is suitable for highly nonideal solutions. A rapid and stable convergence is achieved without the use of damping factors. Numerical examples are presented.