Abstract: Au-K/C catalysts for hydrochlorination of acetylene were prepared by wet impregnation and characterized by XRD, SEM and BET. The results indicate that the active ingredients are highly dispersed on the surface of carrier. Optimized reaction conditions, reaction temperature 170 ℃, space velocity 120 h-1, feed volume ratio (VHCl/VC2H2)1.10, are obtained based on the detailed study of effects of temperature, space velocity, feed ratio and reactants on the performances of Au-K/C catalysts in atmospheric fixed bed reactor. In the optimized reaction conditions, AuK/C catalyst is tested for 120 h in which the acetylene conversion and vinyl chloride (VC) selectivity are over 96.0% and 99.5%, respectively, without significant drop of catalytic activity.