Abstract: Based upon industrial data, a hydrodenitrogenation kinetic model was proposed in this paper. Through analyzing hydrodenitrogenation reaction mechanism, several influence parameters were presented in velocity constant k . These influence parameters in hydrodenitrogenation process mainly included reaction temperature, partial pressure of hydrogen, concentration of hydrogen sulfide in recycling hydrogen, and feed characteristics. While feed characteristics included density, mean boiling point and final boiling point. Velocity constant k was in exponent formula of these influence parameters according Arrhenius equation. The parameters of the model were correlated through practical data, and the obtained results were convinced compared with literatures. Several common work conditions were also predicted by the established model and the predicted results were in correspondence with practical data.