Abstract:
Functionalized poly(ethylene glycol) methyl ether end capped with fivemembered cyclic carbonate (mPEGGC) was synthesized from mPEG, succinic anhydride and glycerol1,2carbonate. Reaction rate constants and activation energy were determined from the model reaction between mPEGGC and amines at different temperatures. The carbonate conversion increased with the reaction time, amine dosage and temperature, while showed a maximum upon increasing the reactant concentration. The activation energy (Ea) in the reaction of mPEGGC with heptyl amine is the lowest(5.63 kJ/mol). The reaction rate constant for mPEGGC with cyclohexyl amine is larger than that with 2aminoheptane at the same temperature.