Abstract: The differential potential and self-renew ability is the most important field in the research of human hematopoietic stem cells(HSCs).In this research,through systematically analysis of the EST((expressed) sequence tags) and SAGE(serial analysis of gene expression) data from HSCs,some molecular markers that were often considered specific in the differential cells of HSCs or other tissue cells were found.In the transcription regulation,anti-RNA probably is of paramount importance in the control of a bio-process.