Abstract: Salvia miltiorrhiza Bge was respectively extracted from the same batch of medicinal material by coupling percolationadsorption and heat extraction method, and the extracts were analyzed by HPLC to observe the influences of different extract methods and temperatures on the content of salvianolic acid B (Sal B), the extraction ratio of Sal B and the chromatography spectrum. The results indicated that there exists the highest content of Sal B in the extracts and few smallmolecular phenolic acid compounds when the coupling percolationadsorption technology was used, while the sort and content of smallmolecular phenolic acids increased with the extract temperature (from 60 ℃ to 100 ℃) if the heat extraction method was applied. The content and extraction ratio of Sal B decreased firstly and increased later with the rising of the extract temperature, and both of them reach the maximum at 100 ℃. It was suggested that the appropriate extraction method and process condition should be chosen according to requirements on quality and safety of the watersoluble extract and preparations of Salvia miltiorrhiza Bge.