美洛昔康和炎痛喜康的合成

吴范宏; 王葆丹; 奚关根

吴范宏, 王葆丹, 奚关根. 美洛昔康和炎痛喜康的合成[J]. 华东理工大学学报（自然科学版）, 2002, (3): 282-284.

引用本文:

吴范宏, 王葆丹, 奚关根. 美洛昔康和炎痛喜康的合成[J]. 华东理工大学学报（自然科学版）, 2002, (3): 282-284.

WU Fan hong *, WANG Bao dan, XI Guan gen. Synthesis of Meloxicam and Piroxicam[J]. Journal of East China University of Science and Technology, 2002, (3): 282-284.

Citation:

WU Fan hong *, WANG Bao dan, XI Guan gen. Synthesis of Meloxicam and Piroxicam[J]. Journal of East China University of Science and Technology, 2002, (3): 282-284.

美洛昔康和炎痛喜康的合成

Synthesis of Meloxicam and Piroxicam

摘要

摘要: 以氯乙酸异丙酯和糖精钠为原料，经过4－氢基－2－甲基－2H－1，2－苯并噻嗪－3－羧酸异丙酯1，1－二氧化物中间体对美洛昔康和炎痛喜康进行合成研究。总由率分别为53．9％和51．9％。

Abstract: Synthesis of meloxicam and piroxicam from isopropyl chloroacetate and saccharin sodium dihydrate, through the intermediate of isopropyl 4 hydroxy 2 methyl 2 H 1,2 benzothiazine 3 carboxylate 1,1 dioxide was realized. The total yield is 53.9% and 51.9%, respectively.

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