Abstract: The starch granules were prepared in fluid bed by tangential spray. The particle size distribution and flowability were selected to evaluate the effects of the formulation factors and process parameters on the granulation. The results show that the flowability and the yield of granule （65-100 mesh）are excellent when the inlet temperature is 70 ℃，blowing rate is 60-70 m3/h， atomization pressure is 0.15 MPa, spray speed is 17.5 g/min, w=3% HPMC K100 as the adhesion agent(mass ratio of adhesion agent to starting materials is 3.0%).